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Updated: Aug 21, 2026

Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
[Case report: nosocomial Ralstonia pickettii infection in neonatal intensive care unit]
Ali K Adiloğlu1, Ali Ayata, Cem Sirin
1Süleyman Demirel Universitesi Tip Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Isparta.
Abstract:
Although Ralstonia pickettii was known as a saprophytic species, it has been isolated in nosocomial infections in recent years. In this case report, R. pickettii infection of a neonate in the neonatal intensive care unit (ICU) was presented. R. pickettii was isolated from the blood cultures of the neonate and also from the incubator and distilled water of the incubator. The isolates revealed identical biochemical and physiological characteristics. The strains were identified by conventional tests and by API ID32 GN system. There was no other newborn infected by R. pickettii in the ICU during the same period. In conclusion, R. picketti should be taken into consideration as an etiologic agent especially in ICU infections. To prevent outbreaks, sterile solutions used for patient care and other possible sources must be investigated regularly.
Insights
Ralstonia pickettii, typically saprophytic, caused a rare neonatal intensive care unit (ICU) infection. The bacterium was found in the infant's blood, incubator, and water, highlighting potential nosocomial risks.
Area of Science:
- Microbiology
- Infectious Diseases
- Neonatal Care
Background:
- Ralstonia pickettii is increasingly recognized as a cause of nosocomial infections.
- Historically considered a non-pathogenic, saprophytic bacterium.
- Neonatal intensive care units (ICUs) are vulnerable to opportunistic infections.
Observation:
- A case of Ralstonia pickettii infection in a neonate within an ICU is reported.
- The bacterium was isolated from the neonate's blood cultures.
- Environmental sources, including the incubator and its distilled water, also yielded R. pickettii isolates.
Findings:
- Biochemical and physiological analyses confirmed identical characteristics among all R. pickettii isolates.
- Conventional tests and the API ID32 GN system were used for strain identification.
- No other neonates in the ICU were infected during the same period, suggesting a localized source.
Implications:
- Ralstonia pickettii should be considered a potential etiologic agent for ICU infections, particularly in neonates.
- Regular monitoring of sterile solutions and patient care equipment is crucial for preventing outbreaks.
- Enhanced surveillance and infection control measures are necessary in high-risk neonatal settings.
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