Related Experiment Video
Updated: Aug 15, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Unilateral and highly asymmetric papilledema in pseudotumor cerebri
1Department of Neurology, UMDNJ/Robert Wood Johnson Medical School, New Brunswick.
Abstract:
I compared six subjects with pseudotumor cerebri and unilateral or highly asymmetric papilledema with 20 such patients with bilateral papilledema. Patients with unilateral papilledema were significantly older than those with bilateral papilledema, but there were no significant differences between the two groups in disease duration, elevation of intracranial pressure, visual fields and acuity, and presence of headaches or transient visual obscurations. I hypothesize that, in patients with unilateral papilledema, one optic nerve is protected from pressure effects by optic nerve sheath anomalies or lamina cribrosa changes due to increased collagen and decreased elasticity with aging.
Related Concept Videos
Glaucoma: Overview
Brain Abscess l: Introduction
Increased Intracranial Pressure l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Cerebral Edema l: Introduction
Cerebral Edema ll: Pathophysiology

