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Updated: Jul 29, 2026

An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy
Published on: January 25, 2019
Idiopathic preretinal fibrosis: a review of 237 cases
A R Pilkerton1, W S Gilbert, L E Perraut
1Retina Group of Washington, Chevy Chase, MD 20815.
Abstract:
We reviewed the charts of 223 patients (236 eyes) with idiopathic preretinal fibrosis, dividing them into two groups: those who only had been observed, and those who, after an observation period, had the membranes surgically removed. All of the patients had been followed from 6 to 120 months (mean, 29 months). Vision in the nonsurgical group slowly deteriorated and was accompanied by metamorphopsia. More rapid visual deterioration occurred in 60 eyes (25%), of which 37 (16%) required surgery. Vision in 78% of the surgical group improved, with the greatest subjective benefit considered to be subsidence of metamorphosia. Vision spontaneously improved in 2.5% of the cases.

