Characterization of a new HLA-DRB1*01 allele (HLA-DRB1*010203) in a Caucasian Italian family by using sequence-based
A Bontadini1, S Manfroi, L Delfino
1Transfusion Service, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Tissue Antigens
|October 22, 2004
Abstract:
We report the identification of an HLA-DRB1*01 nucleotide sequence variant in three members of a Caucasian Italian family by using sequence-based typing. The nucleotide sequence of exon 2 observed in the new allele is identical to that of HLA-DRB1*010201 except in position 189 (codon 34) where the adenine of the consensus was replaced by a guanine and it was designated officially as HLA-DRB1*010203* by the WHO Nomenclature Committee.
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