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Published on: June 28, 2011
Synthesis of potential metabolites of (S)-(-)-bromofosfamide
1Department of Bioorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Lodz, Poland. kmisiura@bio.cbmm.lodz.pl
Die Pharmazie
|October 23, 2004
Abstract:
(S)-(-)-Bromofosfamide, a newly obtained anticancer agent, recently became a subject of phase I clinical trials in Poland. With the aim to study its metabolism in humans using phosphorus nuclear magnetic resonance a group of potential metabolites of this agent was synthesized.