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NF-kappaB signaling: flipping the switch with polyubiquitin chains
Tommer Ravid1, Mark Hochstrasser
1Yale University, Department of Molecular Biophysics & Biochemistry, 266 Whitney Avenue, P.O. Box 208114 New Haven, Connecticut 06520-8114, USA.
Current Biology : CB
|October 23, 2004
Abstract:
Protein modification by ubiquitin has emerged as an important cellular regulatory mechanism. Recent studies illustrate the surprising ways in which polyubiquitin chains are manipulated in the regulation of NF-kappaB signaling.