Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pupillary constriction during forceful eyelid closure.

T A Cox1, K B Digre

  • 1Department of Ophthalmology, University of Utah Medical School, Salt Lake City.

American Journal of Ophthalmology
|February 15, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

History of childhood maltreatment is associated with comorbid depression in women with migraine.

Neurology·2007
Same author

High prevalence of somatic symptoms and depression in women with disabling chronic headache.

Neurology·2007
Same author

Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.

Neurology·2006
Same author

Orbital socket contracture: a complication of inflammatory orbital disease in patients with Wegener's granulomatosis.

The British journal of ophthalmology·2005
Same author

Choroidal neovascular membrane inhibition in a laser treated rat model with intraocular sustained release triamcinolone acetonide microimplants.

The British journal of ophthalmology·2003
Same author

Safety and pharmacokinetics of intravitreal 2-methoxyestradiol implants in normal rabbit and pharmacodynamics in a rat model of choroidal neovascularization.

Experimental eye research·2002
Same journal

Corneal sensitivity changes and nerve plexus abnormalities in noninfectious anterior uveitis.

American journal of ophthalmology·2026
Same journal

Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

American journal of ophthalmology·2026
Same journal

Forging Ahead: The Need for Improved Representation in Academic Ophthalmology.

American journal of ophthalmology·2026
Same journal

Clinical Utility of Ultra-Widefield Swept-Source OCT for Intraocular Tumors: Comparison With Ultrasonography, SD-OCT, and MRI.

American journal of ophthalmology·2026
Same journal

Therapeutic Advances in Corneal Scar management: Topical Treatments, Mesenchymal Cell Therapy and Stromal Transplantation.

American journal of ophthalmology·2026
Same journal

Increased Risk for Ocular Surface Neoplasia in Recipients of Solid Organ Transplant.

American journal of ophthalmology·2026
See all related articles

Forceful eyelid closure can cause pupillary constriction in some individuals. This study found a 30% detection rate, suggesting it may aid in assessing vision but isn't universally effective.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Physiology

Background:

  • Pupillary light reflex is a key indicator of neurological function.
  • Assessing pupillary response is crucial for diagnosing various conditions.
  • Alternative methods to elicit pupillary constriction are of clinical interest.

Purpose of the Study:

  • To investigate pupillary constriction during forceful eyelid closure.
  • To determine the prevalence and characteristics of this pupillary response.

Main Methods:

  • Infrared-sensitive television videography was used to film the right eye.
  • 30 healthy subjects underwent forceful eyelid closure in darkness.
  • Pupillary diameter was analyzed before, during, and after the maneuver.

Related Experiment Videos

Main Results:

  • Clinically detectable pupillary constriction occurred in 30% of subjects.
  • No significant correlation was found between constriction amplitude and age or baseline pupillary diameter.
  • The maneuver did not consistently elicit a detectable pupillary response.

Conclusions:

  • Forceful eyelid closure can induce pupillary constriction in a subset of individuals.
  • This technique may be considered for evaluating patients with impaired pupillary responses.
  • The variability in response suggests limitations for widespread clinical application.