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[Study on extraction technology for extract and flavonoids in Chrysanthemum morifolium by orthogonal design]
Hong Yin1, Yong-Zhou Hu, Xin-Ji Yang
1College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031, China.
Objective:
To ascertain extraction technology condition for extract and flavonoids from Chrysanthum morifoliwn.
Method:
The optimizing ultrasonic extraction condition on the basis of extractive yield and flavonoids were determined by orthogonal design.
Result:
The order of factors which affected the flavonoid extraction was extraction times > ethanol concentration > ultrasonic time > solvent quantity.
Conclusion:
The optimum ultrasonic extractions are A2B3C3D3. Compared with traditional extraction, ultraction method is timesaving, simple to operate, stable and need not be heated.

