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Updated: Aug 21, 2026

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin
R Silva1, T Torrent, R Loureiro
1Ophthalmology Department, Hospital of the University of Coimbra, Coimbra--Portugal. rufino.silva@oftalmologia.co.pt
Purpose:
To report a case of bilateral choroidal neovascularization (CNV) associated with optic nerve drusen (OND) treated with photodynamic therapy (PDT) with verteporfin.
Methods:
A 10-year-old girl with juxtapapillary CNV in the right eye and juxtapapillary and juxtafoveal CNV in the left eye associated with OND underwent PDT with verteporfin in both eyes.
Results:
Visual acuity increased from 20/160 to 20/25 in the right eye and from 20/1000 to 20/25 in the left eye after two sessions of PDT and 2 years of follow-up. CNV showed no leakage after two PDT sessions in both eyes and no recurrence was observed.
Conclusions:
Subfoveal CNV is an uncommon complication of OND and excellent anatomic and functional results can be obtained with PDT.
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