Random genetic drift and selection in a triallelic locus: a continuous diffusion model
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Updated: Aug 18, 2026

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
Published on: July 4, 2007
1Museum of Comparative Zoology, Harvard University, Cambridge, Massachusetts 02138.
Abstract:
The Kolmogorov forward diffusion equation is used to examine the evolution of three alleles at one locus under viability selection and random genetic drift. Separation of variables and Chebyschev approximations are employed to solve this equation for long times. As an example, one artificial viability set is examined in detail; its general implications for the evolution at a triallelic locus are discussed.
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