Related Experiment Video

Updated: Aug 21, 2026

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
10:18

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Published on: February 1, 2022

Survival after simultaneous left ventricular free wall, papillary muscle, and ventricular septal rupture

Peter A Walts1, A Marc Gillinov

  • 1Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

The Annals of Thoracic Surgery
|October 30, 2004
PubMed

Insights

This case report details the first survival of a patient with cardiac rupture at all three common sites following acute myocardial infarction. Early diagnosis via transesophageal echocardiography and prompt surgical intervention were critical for this rare outcome.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Medical Imaging

Background:

  • Acute myocardial infarction (MI) can lead to cardiac rupture, a life-threatening complication.
  • Rupture typically occurs at the left ventricular free wall, interventricular septum, or papillary muscle.
  • Rupture at multiple sites is exceedingly rare and historically associated with non-survival.

Observation:

  • A unique case of a patient experiencing rupture at all three potential cardiac sites simultaneously after acute MI is presented.
  • Transesophageal echocardiography played a crucial role in the rapid and accurate diagnosis of the complex rupture.
  • The patient underwent emergent surgical repair, addressing all three rupture sites.

Findings:

  • Survival following simultaneous rupture at the left ventricular free wall, interventricular septum, and papillary muscle is possible.
  • This case demonstrates the feasibility of surgical correction for extensive cardiac rupture.
  • Successful management required a multidisciplinary approach involving cardiology, cardiac surgery, and advanced imaging.

Implications:

  • This case highlights the importance of considering extensive cardiac rupture in severe MI presentations.
  • Transesophageal echocardiography is vital for diagnosing complex cardiac ruptures.
  • Aggressive surgical management can offer a chance of survival in previously unsurvivable scenarios.
  • Further research into optimal surgical techniques and patient selection for extensive cardiac rupture is warranted.

More Related Videos

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice09:40

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice

Published on: May 13, 2019

Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...