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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
[Obsessive compulsive disorder]
1Institut de Psychiatrie, CHU Brugmann, ULB, Bruxelles.
Abstract:
Obsessive compulsive disorder (OCD) is a disabling psychiatric problem frequently encountered, with a chronic, fluctuating course. Several symptomatic categories are described, depending on the kind of symptoms displayed and on underlying cognitive disturbances and beliefs. OCD has a strong genetic component but environmental factors leading to cerebral lesions in the striatum have also been implicated. Treatment usually associates medication and behavior therapy. It has a favorable impact, most of the time, on the patients' functioning, total remission being rather rare.
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