Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paediatric lung transplantation.

G B Mallory1, T L Spray

  • 1Lung Transplant Program, Texas Children's Hospital, 6621 Fannin, CC 1040.00, Houston, TX 77030, USA. gbmallor@texaschildrenshospital.org

The European Respiratory Journal
|November 2, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A systematic approach to transplanting non-resident, non-citizens in an established US pediatric lung transplant program.

International journal of pediatrics & adolescent medicine·2022
Same author

Haemodynamic characterisation and heart catheterisation complications in children with pulmonary hypertension: Insights from the Global TOPP Registry (tracking outcomes and practice in paediatric pulmonary hypertension).

International journal of cardiology·2015
Same author

Psychological adjustment of pediatric lung transplantation candidates and their parents.

Journal of clinical psychology in medical settings·2013
Same author

Clostridium difficile colitis in children following lung transplantation.

Pediatric transplantation·2010
Same author

Perinatal and early surgical outcome for the fetus with hypoplastic left heart syndrome: a 5-year single institutional experience.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2010
Same author

Long-term impact of respiratory viral infection after pediatric lung transplantation.

Pediatric transplantation·2010
Same journal

Beyond the 5th percentile: rethinking diagnostic thresholds in pulmonary function testing.

The European respiratory journal·2026
Same journal

A Transcriptomic Atlas of Chronic Lung Allograft Dysfunction.

The European respiratory journal·2026
Same journal

Risk of cancer and mortality in patients with interstitial lung diseases: Danish cohort study.

The European respiratory journal·2026
Same journal

Proposing a minimal important difference in NTproBNP in pulmonary arterial hypertension.

The European respiratory journal·2026
Same journal

Unlocking growth potential: Ivacaftor therapy and developmental gains in lung and height in a cohort study of children and young adults with cystic fibrosis.

The European respiratory journal·2026
Same journal

Decoding the Lymphangioleiomyomatosis (LAM) Niche Microenvironment <i>via</i> Integrative Analysis of Single Cell Multiomics and Spatial Transcriptomics.

The European respiratory journal·2026
See all related articles

Pediatric lung transplantation is uncommon but essential for children with specific conditions like cystic fibrosis. Key differences in surgical approach and higher complication rates, including bronchiolitis obliterans, are noted in pediatric patients.

Area of Science:

  • Pediatric Pulmonology
  • Thoracic Surgery
  • Transplant Immunology

Background:

  • Lung transplantation in pediatric populations (infants, children, adolescents) has been performed since 1990 but remains less common than in adults.
  • While indications are similar to adults, distinct disease entities drive pediatric lung transplants, including congenital heart disease-associated pulmonary vascular disease and cystic fibrosis.

Purpose of the Study:

  • To review the unique aspects of lung transplantation in pediatric patients compared to adults.
  • To highlight differences in indications, surgical techniques, donor types, and post-transplant complications.

Main Methods:

  • Review of pediatric lung transplant literature and comparison with adult transplant data.
  • Analysis of distinct disease etiologies and surgical approaches in pediatric recipients.

Related Experiment Videos

Main Results:

  • Pediatric lung transplantation utilizes cardiopulmonary bypass more frequently and favors bilateral over single lung transplants.
  • Living donor lung transplantation is proportionally more common in children and adolescents.
  • Post-transplant complications, including viral infections, lymphoproliferative disease, and bronchiolitis obliterans, are more frequent and severe in pediatric patients.

Conclusions:

  • Pediatric lung transplantation involves unique surgical strategies and presents distinct challenges regarding complications.
  • Bronchiolitis obliterans remains a significant limiting factor for long-term survival and quality of life in pediatric lung transplant recipients, mirroring adult outcomes.