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Combined effects of smoking and hypercholesterolemia on inflammatory process, thrombosis/fibrinolysis system, and
Charalambos Antoniades1, Dimitris Tousoulis, Carmen Vasiliadou
1Department of Cardiology, Athens University Medical School, Athens, Greece.
Abstract:
The combined effects of smoking and hypercholesterolemia on the inflammatory process, the thrombosis/fibrinolysis system, and forearm hyperemic response were investigated. It was shown that smokers with hypercholesterolemia (n = 25) had a reduced and delayed forearm hyperemic response compared with healthy smokers (n = 24), patients with hypercholesterolemia (n = 26), and healthy controls (n = 75; p <0.01 for all). This phenomenon was associated with a respective increase in the inflammatory process and changes in the thrombosis/fibrinolysis system.
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