Related Experiment Videos
[Tricholoma equestre--animal toxicity study].
Zygmunt Chodorowski1, Małgorzata Sznitowska, Marek Wiśniewski
1I Klinika Chorób Wewnetrznych i Ostrych Zatruć, Akademii Medycznej w Gdańsku. jsanand@amedec.amg.gda.pl
Przeglad Lekarski
|November 4, 2004
Summary
This study found that Tricholoma equestre mushroom extracts, stored for 12 months at -20°C, did not cause muscle damage (rhabdomyolysis) in mice. The creatine kinase levels remained normal across all tested mushroom extract groups.
Area of Science:
- Mycology
- Toxicology
- Biochemistry
Context:
- Tricholoma equestre, a widely consumed mushroom, has been associated with potential toxicity.
- Understanding the safety of long-term stored mushroom extracts is crucial for culinary and medicinal use.
Purpose:
- To evaluate the potential toxicity of stored Tricholoma equestre mushroom extracts.
- To assess the impact of mushroom extracts on muscle integrity by measuring serum creatine kinase activity.
Summary:
- Male BALB/c mice were administered various Tricholoma equestre extracts (powder, aqueous, chloroform-methanol) and controls for three days.
- Serum creatine kinase (CK) levels were measured 72 hours post-administration.
- No significant elevation in CK levels was observed in mice treated with mushroom extracts compared to the water control group.
Impact:
- The findings suggest that Tricholoma equestre mushroom extracts stored under specified conditions do not induce rhabdomyolysis in mice.
- This research contributes to the safety assessment of edible mushrooms and their processed forms.