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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Progressive stroke due to essential thrombocythemia

Konstantinos N Vemmos1, Konstantinos Spengos, Georgios Tsivgoulis

  • 1Department of Clinical Therapeutics, Acute Stroke Unit, University of Athens Medical School, Alexandra Hospital, Vasilissis Sofias 80, 11528 Athens, Greece.

European Journal of Internal Medicine
|November 4, 2004
PubMed

We report a case of progressive stroke, due to an intracranial thrombosis, leading to a high-grade stenosis of the internal carotid artery (ICA). Essential thrombocythemia (ET) was identified as the cause of thrombosis. Effective anticoagulation in the acute phase of cerebral ischemia prevented further thrombus organization and total vessel obstruction. After clinical improvement and normalization of platelet counts under hydroxyurea, anticoagulation was stopped and antiplatelet agents were subsequently administered.

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