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Updated: Aug 14, 2026

Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro
Published on: October 13, 2023
[Experimental study on treatment of minimal change nephropathy with niaozhuoqing]
Huanyu Li1, Hongzhu Deng, Caiyun Wang
1Guangzhou Sanatorium of PLA, Guangzhou 510515.
Objective:
To study the therapeutic effect of niaozhuoqing on minimal change nephropathy (MCN) in rats.
Methods:
The MCN rat model was induced by intravenous injection of adriamycin. The effect of treatment on 24h urine protein, serum protein, lipid metabolism, malondialdehyde (MDA), superoxide dismutase (SOD) in serum, and renal histopathological changes were observed.
Results:
Niaozhuoqing could decrease the contents of proteinuria, blood lipid and MDA in serum, increase serum protein, SOD level and pathologically restore the glomeruli.
Conclusion:
Niaozhuoqing has good effects on MCN, which probably related to decrease serum lipids level and reduce oxygen free radicals.
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