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Updated: Aug 21, 2026
13:18
Understanding Cerebellar Pattern Formation
Published on: November 1, 2007
[An enigmatic disease in Gregor Mendel's life]
1Université Paris 7, boîte courrier 7077, 2, place Jussieu, 75251 Paris, France. nivet@paris7.jussieu.fr
Medecine Sciences : M/S
|November 5, 2004
Abstract:
The great value of the experimental and theoretical work of Gregor Mendel has been recognized more than thirty five years after its publication; in this article, we suggest that his personality has still to be rediscovered.
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01:43Incomplete Dominance
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
01:20Monohybrid Crosses
Overview
01:49Law of Segregation
When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
02:03Law of Independent Assortment
While Mendel’s Law of Segregation states that the two alleles for one gene are separated into different gametes, a different question of how different genes are inherited remains. For example, is the gene for tall plants inherited with the gene for green peas? Mendel asked this question by experimenting with a dihybrid cross; a cross in which both parents are homozygous for two distinct traits resulting in an F1 generation that are heterozygous for both traits.
01:39Chromosomal Theory of Inheritance
In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
01:18Dihybrid Crosses
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