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Updated: Jul 28, 2026

Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
The utility of superparamagnetic contrast agents in MRI: theoretical consideration and applications in the
Atle Bjørnerud1, Lars Johansson
1Department of Radiology, Rikshospitalet University Hospital, N-0027 Oslo, Norway. atle.bjornerud@rikshospitalet.no
Abstract:
This review will discuss the in vivo physical chemical relaxation properties of superparamagnetic iron oxide particles. Various parameters such as size, magnetization, compartmentalization and water exchange effects and how these alter the behavior of the iron oxide particles in an in vitro vs an in vivo situation with special reference to the cardiovascular system will be exemplified. Furthermore, applications using iron oxide particles for vascular, perfusion and viability imaging as well as assessment of the inflammatory status of a given tissue will be discussed.
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