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Updated: Aug 21, 2026

In vitro Organoid Culture of Primary Mouse Colon Tumors
Published on: May 17, 2013
The pathophysiology, clinical presentation, and diagnosis of colon cancer and adenomatous polyps
1Division of Gastroenterology, Department of Medicine, Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141-3098, USA. mscappell@yahoo.com
Abstract:
A review of the pathophysiology, clinical presentation, and diagnosis of colon cancer and colonic polyps is important and timely. This field is rapidly changing because of breakthroughs in the molecular basis of carcinogenesis and in the technology for colon cancer detection and treatment. This article reviews colon cancer and colonic polyps, with a focus on recent dramatic advances, to help the pri-mary care physician and internist appropriately refer patients for screening colonoscopy and intelligently evaluate colonoscopic findings to reduce the mortality from this cancer.
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