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Updated: Aug 21, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Effects of cured dentin bonding materials on human monocyte viability
A Vahid1, J Hadjati, H Kermanshah
1Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. vahidala@sina.tums.ac.ir
Objectives:
Dentin Bonding Agents (DBAs) have been proposed as root-end filling materials. This study examined the effect of polymerized DBAs on human monocyte viability.
Study Design:
Monocytes were directly isolated from peripheral blood and being exposed to cured Scotch bond I (Single Bond) and Prime & Bond in different time intervals (36 and 72 hours). The viability of monocytes was determined by MTT assay.
Results:
Viability of the cells was time dependent. There was no significant difference between the effect of 2 DBAs on monocytes.
Conclusion:
Results indicate that DBAs in polymerized form can alter the viability of monocytes and decrease it within time.
