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Residential mobility during pregnancy.

Deshayne B Fell1, Linda Dodds, Will D King

  • 1Perinatal Epidemiology Research Unit, Department of Obstetrics and Gynecology, Dalhousie University, Halifax, Nova Scotia B3K 6R8, Canada. Deshayne.Fell@iwk.nshealth.ca

Paediatric and Perinatal Epidemiology
|November 13, 2004
PubMed
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Maternal residential mobility during pregnancy is common and can lead to exposure misclassification in environmental health studies. Factors like income, age, and BMI influence this mobility, impacting study accuracy.

Area of Science:

  • Environmental epidemiology
  • Reproductive health

Background:

  • Maternal residence at delivery is often used to assign environmental exposure levels in epidemiological studies.
  • Residential mobility can lead to exposure misclassification, potentially biasing results.

Purpose of the Study:

  • To examine the prevalence and predictors of maternal residential mobility during pregnancy.
  • To assess the potential for exposure misclassification in environmental health studies due to residential changes.

Main Methods:

  • Analysis of data from 398 control subjects in a stillbirth case-control study.
  • Comparison of demographic, lifestyle, medical, pregnancy, and environmental factors between women who moved and those who did not.
  • Bivariable and multivariable log binomial regression analyses to identify risk factors for mobility.

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Main Results:

  • Twelve percent of women moved at least once during pregnancy; most moves were within the same municipality.
  • Low family income, younger maternal age, unmarried status, and tobacco use were associated with increased mobility.
  • Higher prepregnancy body mass index (BMI) and folic acid use were associated with decreased mobility.

Conclusions:

  • Maternal residential mobility during pregnancy is prevalent enough to cause significant exposure misclassification in environmental studies.
  • Risk factors for mobility (e.g., income, age, BMI) may overlap with risk factors for adverse pregnancy outcomes, necessitating consideration of differential misclassification.