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Published on: August 28, 2018

Bilateral diagonal earlobe crease and coronary artery disease: a significant association

Harun Evrengül1, Dursun Dursunoğlu, Asuman Kaftan

  • 1Department of Cardiology, Pamukkale University School of Medicine, Denizli, Turkey. harunevrengul@hotmail.com

Dermatology (Basel, Switzerland)
|November 13, 2004
PubMed

Insights

A diagonal earlobe crease (ELC) is linked to coronary artery disease (CAD). This study found bilateral ELC is an independent predictor of CAD, suggesting its use as a diagnostic tool.

Area of Science:

  • Cardiology
  • Dermatology
  • Medical Diagnostics

Background:

  • The link between diagonal earlobe crease (ELC) and coronary artery disease (CAD) is debated.
  • Further research is needed to clarify this association.

Purpose of the Study:

  • To investigate the relationship between bilateral ELC and the presence of CAD.
  • To determine if ELC can serve as a diagnostic indicator for CAD.

Main Methods:

  • Examined 415 patients for bilateral ELC, CAD via angiography, and coronary risk factors.
  • Classified patients into two groups based on CAD presence.

Main Results:

  • Bilateral ELC showed a significant positive correlation with CAD, hypertension, age, male gender, smoking, and family history.
  • ELC was identified as an independent predictor of CAD.
  • Diagnostic values for bilateral ELC in detecting CAD: sensitivity 51.3%, specificity 84.8%, PPV 89.4%, NPV 41.2%.

Conclusions:

  • Bilateral ELC is significantly associated with CAD and its risk factors.
  • Bilateral ELC is a valuable dermatological marker for CAD.
  • ELC may be a useful tool in clinical patient assessment for CAD.
Abstract

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