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Updated: Aug 21, 2026

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
Published on: September 8, 2023
Topography-induced polarization anisotropy in mesoscale structures
Hsieh-Li Chou1, Yi-Chun Chen, Pei-Kuen Wei
1Institute of Applied Science and Engineering Research, Academia Sinica, Taipei, Taiwan.
Abstract:
Optical polarization anisotropy on the surface of subwavelength air-dielectric structures was studied by polarization-modulation near-field optical microscopy. A large degree of polarization anisotropy was measured in the higher topographic region of transparent gratings. In two-dimensional air-hole arrays, the largerpolarization anisotropy occurs in the dielectric regions. Both dielectric and air regions have a 90 degrees difference in the directions of maximum transmission. From calculations with the finite-difference time-domain method, we verified that diffracted light from the mesoscale topographic edges contributes to polarization anisotropy and directional differences.
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