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Clostridial myonecrosis resulting from subcutaneous epinephrine suspension injection
L F Hallagan1, J L Scott, B C Horowitz
1Department of Emergency Medicine, George Washington University Medical Center, Washington, DC.
Annals of Emergency Medicine
|April 1, 1992
Abstract:
A 32-year-old asthmatic man developed a life-threatening Clostridium perfringens infection after subcutaneous epinephrine suspension injection. Extensive surgical debridement, including forequarter amputation, hyperbaric oxygen therapy, and appropriate antibiotics were used as life-saving measures. The patient made a fair functional recovery. We could find no previously reported cases of gas gangrene following subcutaneous injection in otherwise healthy individuals. The pathogenesis and treatment of this infection are discussed.