Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computerized nipple identification for multiple image analysis in computer-aided diagnosis.

Chuan Zhou1, Heang-Ping Chan, Chintana Paramagul

  • 1Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109, USA. chuan@umich.edu

Medical Physics
|November 17, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physics-informed data augmentation to simulate low dose CT scans: Application to lung nodule detection.

Medical physics·2026
Same author

Synthetic data in radiological imaging: current state and future outlook.

BJR artificial intelligence·2026
Same author

Task-Based Sampling of Patient Data for Rigorous Machine Learning/AI Performance Assessment.

Journal of imaging informatics in medicine·2026
Same author

Statistical testing of agreement in overlap-based performance between an AI segmentation device and a multi-expert human panel without requiring a reference standard.

Journal of medical imaging (Bellingham, Wash.)·2025
Same author

A data-driven framework for identifying patient subgroups on which an AI/machine learning model may underperform.

NPJ digital medicine·2024
Same author

Bias Amplification to Facilitate the Systematic Evaluation of Bias Mitigation Methods.

IEEE journal of biomedical and health informatics·2024
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

This study presents an automated method for nipple detection on mammograms, improving breast cancer diagnosis. The system accurately identifies visible nipples and reasonably estimates invisible ones, aiding computer-aided diagnosis.

Area of Science:

  • Medical Imaging
  • Radiology
  • Computer-Aided Diagnosis (CAD)

Background:

  • Mammogram correlation enhances breast cancer diagnosis accuracy.
  • Nipple location is a key landmark for aligning multiple mammograms.
  • Accurate nipple identification is challenging due to image quality and projection variations, often making nipples nearly invisible.

Purpose of the Study:

  • To develop a computerized method for automatic nipple location identification on digitized mammograms.
  • To improve the reliability of nipple detection for multi-view mammogram analysis.

Main Methods:

  • Breast boundary extraction using gradient-based tracking.
  • Geometric convergence analysis to define nipple search regions.
  • A two-stage detection method utilizing gray level, shape, and texture features.

Related Experiment Videos

  • Rule-based confidence analysis for final nipple location determination.
  • Main Results:

    • The algorithm detected 89.37% of visible nipples and 69.74% of invisible nipples within 1 cm of the gold standard in the training set.
    • In the test set, 92.28% of visible nipples and 53.62% of invisible nipples were detected within 1 cm.
    • High accuracy was achieved for visible nipples, with reasonable estimation for invisible ones.

    Conclusions:

    • Automated nipple detection is feasible and accurate on digitized mammograms.
    • This method enhances the potential for automated analysis of multiple mammograms.
    • Automated nipple detection is a crucial step towards advancing computer-aided diagnosis systems.