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[Lung carcinosarcoma. A case report].

F El Mezni1, N Mrabet, B Smati

  • 1Service d'Anatomie Pathologique, Hôpital Abderraman-Mami, 2080 L'Ariana/Tunis, Tunisie. faouzi.elmezni@rns.tn

Revue De Pneumologie Clinique
|November 17, 2004
PubMed
Summary
This summary is machine-generated.

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Lung carcinosarcoma, a rare and aggressive cancer with epithelial and malignant mesenchymal parts, has a poor prognosis. This case highlights the diagnostic process and rapid, fatal outcome in a 71-year-old male patient.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Lung carcinosarcoma is a rare, highly malignant neoplasm.
  • Its histogenesis remains largely unknown.
  • Characterized by both epithelial carcinomatous and malignant mesenchymal components with heterologous tissue.

Observation:

  • A case of lung carcinosarcoma in a 71-year-old male is presented.
  • The patient experienced chest pain as the primary symptom.
  • The outcome was rapidly fatal, with death occurring three months after presentation.

Findings:

  • Diagnosis was established via transparietal biopsy.
  • Immunohistochemistry on the surgical resection specimen confirmed the diagnosis.
  • The tumor exhibited a biphasic pattern, typical of carcinosarcoma.

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Implications:

  • Lung carcinosarcoma carries a very poor prognosis, with less than 10% survival at two years post-surgery.
  • Early and accurate diagnosis, including immunohistochemistry, is crucial.
  • This case underscores the aggressive nature and limited treatment options for this rare lung cancer.