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Intratympanic steroid treatment: a review
Karen Jo Doyle1, Christopher Bauch, Robert Battista
1Department of Otolaryngology--Head and Neck Surgery, University of California Davis, Sacramento, California 95817, USA. karen.doyle@ucdmc.ucdavis.edu
Summary
Intratympanic steroids show weak promise for sudden hearing loss when oral steroids fail. However, evidence for Meniere
Area of Science:
- Otolaryngology
- Pharmacology
- Evidence-based Medicine
Background:
- Meniere's disease and sudden sensorineural hearing loss are debilitating conditions.
- Intratympanic steroid injections are a potential treatment modality.
Purpose of the Study:
- To review existing literature on intratympanic steroid use for Meniere's disease and sudden hearing loss.
- To provide recommendations based on current evidence.
Main Methods:
- Comprehensive literature search of PubMed, Medline Plus, and Web of Science (1996-2003).
- Analysis limited to retrospective case series and uncontrolled prospective cohort studies.
Main Results:
- Weak recommendation for intratympanic steroids in sudden hearing loss if oral steroids are ineffective or contraindicated.
- Insufficient evidence to support intratympanic steroid efficacy for Meniere's disease or tinnitus.
Conclusions:
- Further high-quality research is essential to determine the efficacy of intratympanic steroids for Meniere's disease.
- Current evidence for sudden hearing loss is limited, warranting cautious application.