Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Luteal phase defect: myth or reality.

Orhan Bukulmez1, Aydin Arici

  • 1Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA.

Obstetrics and Gynecology Clinics of North America
|November 20, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal exposure to fine particulate matter and pregnancy outcomes in women undergoing <i>in vitro</i> fertilization: A multicenter retrospective study.

Eco-Environment & Health·2026
Same author

Melatonin enhances vitrified mouse blastocyst development by mitigating oxidative stress and preserving mitochondrial function.

Molecular human reproduction·2025
Same author

Identification and Validation of RPL7 and RCCD1 as Potential Biomarkers Associated with Immune Infiltration in Patients with Thin Endometrium.

Reproductive sciences (Thousand Oaks, Calif.)·2025
Same author

Condensate-forming eIF4ET ensures adequate levels of meiotic proteins to support oocyte storage.

Life science alliance·2025
Same author

Corrigendum to "Risk analysis of torsion and malignancy for adnexal masses during pregnancy" (Fertil Steril 2009;91:1895-902).

Fertility and sterility·2025
Same author

Melatonin Rescues Hyperacetylation of Liver and Impaired Enzymatic Activities of Mitochondrial in IVF Offspring.

Reproductive sciences (Thousand Oaks, Calif.)·2025
Same journal

Bridging Science and Practice in Gender-Affirming Care: A Compendium for Gynecologists.

Obstetrics and gynecology clinics of North America·2026
Same journal

Evidence, Clinical Expertise, and Research Gaps in Gender-Affirming Care.

Obstetrics and gynecology clinics of North America·2026
Same journal

Evaluation and Management of the Pediatric Gender-Diverse Patient.

Obstetrics and gynecology clinics of North America·2026
Same journal

Expanding Access to Cervical Cancer Screening for Transgender and Nonbinary Individuals.

Obstetrics and gynecology clinics of North America·2026
Same journal

Updates on Breast Cancer Screening and Special Considerations for Transgender Men and Women.

Obstetrics and gynecology clinics of North America·2026
Same journal

Contraceptive Needs of the Transmasculine Patient.

Obstetrics and gynecology clinics of North America·2026
See all related articles

Diagnosis of luteal phase defect (LPD) is controversial and lacks evidence linking it to infertility or recurrent pregnancy loss. Current diagnostic and treatment efforts for LPD are not justified in clinical practice.

Area of Science:

  • Reproductive endocrinology
  • Clinical obstetrics and gynecology

Background:

  • Luteal phase defect (LPD) is a debated clinical diagnosis.
  • Uncertainties exist regarding LPD diagnosis and its association with reproductive issues.

Purpose of the Study:

  • To evaluate the clinical validity and justification of diagnosing luteal phase defect (LPD) in patients experiencing infertility or recurrent abortion.

Main Methods:

  • Review of existing research and clinical evidence regarding the diagnosis and treatment of LPD.
  • Analysis of the association between LPD, infertility, and recurrent pregnancy loss.

Main Results:

  • Convincing evidence supporting LPD diagnosis in research settings, but its clinical validity remains controversial.

Related Experiment Videos

  • Lack of strong evidence linking LPD to infertility and recurrent abortion.
  • Treatment options for diagnosed LPD are empiric, similar to unexplained infertility.

    • Conclusions:

    • The clinical diagnosis of luteal phase defect (LPD) is not well-supported by current evidence.
    • Diagnostic efforts for LPD in patients with infertility or recurrent abortion are not justified.
    • Focus should be on established causes and treatments for infertility and recurrent pregnancy loss.