Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sentinel lymph node biopsy after neoadjuvant chemotherapy.

Seok Hyung Kang1, Jae Hee Kang, Eun A Choi

  • 1National Cancer Center, Madu-1-dong 809,san-gu, Goyang-si, Gyeonggi-do, 411-769, Korea. eunsook@ncc.re.kr.

Breast Cancer (Tokyo, Japan)
|November 20, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcending genome-wide association studies to create useful multi-omic views of glaucoma.

Progress in retinal and eye research·2026
Same author

Vitamin/mineral and non-vitamin/non-mineral supplement use of breast cancer survivors in Korea.

Nutrition research and practice·2026
Same author

Integrated tissue and serum proteomics on magnet-guided photothermal therapy using Au/Fe/Au trilayer nanodiscs.

Scientific reports·2025
Same author

ChatGPT-Assisted Glaucoma Diagnosis: A Health-Equitable Multi-Ancestry Analysis Using Visual Field and Optical Coherence Tomography Data.

American journal of ophthalmology·2025
Same author

Distinct urinary exosomal microRNAs as biomarkers for differentiating premature ovarian insufficiency and menopause.

Journal of ovarian research·2025
Same author

Moderating effects of social capital on the relationship between fear of falling and depressive symptoms among community-dwelling older adults.

Archives of public health = Archives belges de sante publique·2025

Sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy is accurate and feasible. This study confirms SLNB

Area of Science:

  • Oncology
  • Surgical Oncology
  • Breast Cancer Research

Background:

  • Neoadjuvant chemotherapy is increasingly used for breast cancer.
  • Sentinel lymph node biopsy (SLNB) is a standard staging procedure.
  • Evaluating SLNB after neoadjuvant chemotherapy is crucial for treatment planning.

Purpose of the Study:

  • To assess the feasibility and accuracy of sentinel lymph node biopsy (SLNB) in breast cancer patients treated with neoadjuvant chemotherapy.
  • To compare current findings with existing literature on SLNB after neoadjuvant chemotherapy.

Main Methods:

  • A prospective study of 80 breast cancer patients undergoing SLNB followed by axillary lymph node dissection (ALND) after neoadjuvant chemotherapy.
  • A systematic literature search using MEDLINE with keywords: breast cancer, sentinel lymph node biopsy, and neoadjuvant chemotherapy.

Related Experiment Videos

Main Results:

  • Tumor downstaging observed in 52.6% of patients; pathologic complete response (pCR) in 11.3% and partial response (pPR) in 41.3%.
  • SLNB was successful in 76.3% of patients with a false negative rate of 7.3% and accuracy of 95.1%.
  • Literature review indicated feasibility and accuracy of SLNB post-neoadjuvant chemotherapy with identification rates of 82%-100%.

Conclusions:

  • Sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy is accurate and feasible in breast cancer management.
  • SLNB can be a reliable alternative to axillary lymph node dissection (ALND) in select patients.
  • Findings support the integration of SLNB into treatment protocols for patients receiving neoadjuvant chemotherapy.