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[The functional condition of the immune system and the lymphocytes' hemopoiesis-modulating properties]

V A Chreshnev, B G Iushkov, I G Daniliova

    Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
    |November 24, 2004
    PubMed

    Donor splenocytes and timocytes have an ability to stimulate erythropoesis after massive blood-letting. Changing of functional state of the immune system by means of immune modulators action affects the character and expressiveness of hemopoiesis regulation function of lymphocytes. Splinocytes and thymocytes depress granulocytopoiesis in the recipients' bone marrow after activation by T- and B-lymphocytes. The activation of B-lymphocytes determines the cells' capacity to increase concentration of thrombocytes in the blood. Donor thymocytes can activate erythropoiesis and granulocytopoiesis after macrophages stimulation.

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