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Multi-slice CT of thyroid nodules: comparison with ultrasonography
Satoko Ishigaki1, Kazuhiro Shimamoto, Hiroko Satake
1Department of Radiology, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan.
Radiation Medicine
|November 24, 2004
Summary
Ultrasonography (US) is superior to multi-slice computed tomography (MSCT) for diagnosing thyroid nodules. However, MSCT aids in evaluating tumor extension in advanced thyroid cancer cases.
Area of Science:
- Radiology
- Oncology
- Endocrinology
Background:
- Thyroid nodules are common, and differentiating benign from malignant types is crucial.
- Accurate tumor staging, including assessment of extension, impacts treatment decisions.
Purpose of the Study:
- To compare the diagnostic utility of multi-slice computed tomography (MSCT) and ultrasonography (US) for thyroid nodules.
- To evaluate the effectiveness of MSCT and US in assessing thyroid tumor extension.
Main Methods:
- Thirty patients with thyroid nodules underwent both MSCT and US.
- MSCT utilized contrast enhancement with 3D shaded volume rendering (SVR) and multiplanar reconstruction (MPR).
- US employed a 7.5 MHz annular array probe; image interpretation used a three-point scale and kappa statistic.
Main Results:
- US demonstrated higher sensitivity (85.7%) than MSCT (78.6%) in differentiating benign from malignant thyroid nodules.
- Discrepancies were noted in assessing nodule homogeneity and fibrous capsule presence.
- MSCT's MPR was more accurate than US in detecting extracapsular invasion in two advanced (T4) cases.
Conclusions:
- US is the preferred imaging modality for the differential diagnosis of thyroid nodules.
- MSCT offers value in evaluating the extent of advanced thyroid cancer, particularly for extracapsular invasion.