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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Ectodermal odontogenic tumours: analysis of 197 Nigerian cases
K E Adebiyi1, O Odukoya, E O Taiwo
1Department of Oral Biology and Pathology, School of Dental Sciences, College of Medicine, University of Lagos, Lagos, Nigeria. kenad@justice.com
Abstract:
This article presents a clinico-pathologic analysis of 197 cases of ectodermal odontogenic tumours archived in the Lagos University Teaching Hospital, Lagos Nigeria over a 21-year period. They were categorized according to the WHO classification of odontogenic tumours. Of the 197 cases, 182 (92.3%) were benign while 15 (7.6%) were malignant. Central ameloblastoma, which accounted for 88.3% in this series, was the most common benign neoplasm demonstrating predilection for males (58.6%) and the mandible (83.3%). The mean age of occurrence (+/-SD) was 31.00 +/- 13.9 (range 9-82 years). Similarly ameloblastic carcinoma was the most prevalent malignant tumour (5.6%) with a predilection for females (63.6%) and the mandible (81.8%). The mean age of occurrence (+/-SD) was 30.1+/- 20.7 (range 16-85) years. Follicular ameloblastoma was found to be the commonest histologic subtype seen in Nigeria.
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