Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acne: inflammation.

Mark D Farrar1, Eileen Ingham

  • 1Skin Research Centre, Division of Microbiology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.

Clinics in Dermatology
|November 24, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Skin <i>Staphylococcus</i> species differentially modulate keratinocyte cytokine secretion in response to UVB.

Applied and environmental microbiology·2026
Same author

Omalizumab Therapy Results in Defined Behavioural Changes and Improvements in Quality of Life in Solar Urticaria.

Photodermatology, photoimmunology & photomedicine·2026
Same author

Solar urticaria involves rapid mast cell STAT3 activation and neutrophil recruitment, with FcεRI as an upstream regulator.

The Journal of allergy and clinical immunology·2024
Same author

Clinicophotobiological Characterization of Photoaggravated Atopic Dermatitis.

JAMA dermatology·2022
Same author

Repopulation of decellularised porcine pulmonary valves in the right ventricular outflow tract of sheep: Role of macrophages.

Journal of tissue engineering·2022
Same author

The effect of decellularisation on the real time mechanical fatigue of porcine aortic heart valve roots.

PloS one·2022
Same journal

Letter to the editor in reply to "Ethics of Rising Trends in Dermatology Publications Using Large-Scale Databases".

Clinics in dermatology·2026
Same journal

Ethics of suggesting image-guided superficial radiation therapy on the pathology report.

Clinics in dermatology·2026
Same journal

Tanorexia: The Psychodermatology of Compulsive Tanning.

Clinics in dermatology·2026
Same journal

Ear manifestations of connective tissue diseases: A dermatologic, histopathologic, and clinicopathologic review.

Clinics in dermatology·2026
Same journal

Discovery of an intravenous drug injection site: A meticulous cutaneous examination provides the forensic dermatologic clue to a diagnosis of homicide.

Clinics in dermatology·2026
Same journal

Sherlock Holmes and the mystery of the deadly diet.

Clinics in dermatology·2026
See all related articles

Inflammatory acne vulgaris causes significant patient distress and scarring. While Propionibacterium acnes is linked to acne, its exact role in the inflammatory process and immune system interaction requires further study.

Area of Science:

  • Dermatology
  • Microbiology
  • Immunology

Background:

  • Acne vulgaris presents with inflammatory lesions causing pain, disfigurement, and psychological distress.
  • A significant percentage of acne patients develop scarring, leading to long-term cosmetic and emotional issues.
  • The underlying mechanisms driving inflammatory acne lesion development are not fully understood.

Purpose of the Study:

  • To investigate the role of Propionibacterium acnes in the pathogenesis of inflammatory acne vulgaris.
  • To elucidate the interaction between Propionibacterium acnes and the human immune system in the context of acne.

Main Methods:

  • Clinical characterization of inflammatory acne lesions.
  • Microbiological analysis of cutaneous microflora.

Related Experiment Videos

  • Immunological assays to assess host response to Propionibacterium acnes.

    • Main Results:

    • Propionibacterium acnes is consistently associated with inflammatory acne lesions.
    • This bacterium appears to play a significant role in triggering the inflammatory response.
    • Further research is needed to fully understand its precise contribution and immune interactions.

    Conclusions:

    • Propionibacterium acnes is a key factor in the inflammatory processes of acne vulgaris.
    • Understanding its interaction with the immune system is crucial for developing targeted acne therapies.
    • Further elucidation of these mechanisms may lead to improved treatment strategies for acne and its sequelae.