Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Infection in sickle cell disease].

Emmanuelle Lesprit1, Philippe Lesprit

  • 1Service de pédiatrie, hôpital intercommunal de Créteil.

La Revue Du Praticien
|November 24, 2004
PubMed
Summary

Bacterial infections, especially pneumococcal bacteremia, pose a severe risk for individuals with sickle cell disease throughout their lives. Prevention strategies focus on vaccination and prophylactic antibiotics to reduce this significant threat.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bacterial epidemiology of male urinary tract infections in France: An expert review.

Infectious diseases now·2026
Same author

Which investigations should be performed after a first episode of urinary tract infection in men?

Infectious diseases now·2026
Same author

Updated guidelines for management of community-acquired urinary tract infections in adult men by the French infectious disease society (SPILF).

Infectious diseases now·2026
Same author

Characteristics and outcome determinants in children, adolescents and young adults who failed tisagenlecleucel for B-cell acute lymphoblastic leukemia.

Leukemia·2026
Same author

Antibiotic prophylaxis For Urologic Surgery.

Anaesthesia, critical care & pain medicine·2026
Same author

Efficacy of antimicrobial stewardship indicators in assessing the impact of a regional antibiotic therapy center in primary care and nursing homes.

Infectious diseases now·2025

Area of Science:

  • Infectious Diseases
  • Hematology
  • Pediatrics

Context:

  • Sickle cell disease (SCD) patients exhibit a heightened susceptibility to bacterial infections.
  • Pneumococcal bacteremia presents a particularly grave threat to young children with SCD.
  • The risk of bacterial infections, including nosocomial infections, extends into adulthood for SCD patients.

Purpose:

  • To highlight the increased risk of bacterial infections in sickle cell disease patients.
  • To emphasize the severity of pneumococcal bacteremia in pediatric SCD populations.
  • To underscore the persistent risk and specific challenges in adult SCD patients.

Summary:

  • Bacterial infections are a common and serious complication in individuals with sickle cell disease.
  • Pneumococcal bacteremia is a critical concern, especially in young children, but the risk continues into adulthood.
  • Preventive measures are crucial, involving vaccination and prophylactic antibiotics against pneumococcal disease.

Impact:

  • Informing healthcare providers about the lifelong vulnerability of SCD patients to bacterial infections.
  • Guiding the implementation of targeted preventive strategies, including vaccination and antibiotic prophylaxis.
  • Improving patient outcomes by reducing the incidence and severity of bacterial infections in sickle cell disease.

Related Experiment Videos