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Updated: Aug 16, 2026

Murine Left Anterior Descending (LAD) Coronary Artery Ligation: An Improved and Simplified Model for Myocardial Infarction
Published on: April 2, 2017
Thrombosed right coronary artery aneurysm presenting as a myocardial mass
Scott Gottesfeld1, Amgad N Makaryus, Balveen Singh
1Division of Cardiology, North Shore Long Island Jewish Health System, New Hyde Park, NY 11040, USA.
Insights
Coronary artery aneurysms, rare dilations of coronary arteries, can mimic myocardial masses. This case highlights a thrombosed right coronary artery aneurysm presenting as an intramyocardial mass after myocardial infarction.
Area of Science:
- Cardiology
- Vascular Medicine
- Diagnostic Imaging
Background:
- Coronary artery aneurysms (CAAs) are rare vascular abnormalities, defined by significant dilatation of coronary arteries, occurring in 1.5% to 5% of the population.
- Pathologically, CAAs result from medial destruction and arterial wall thinning, leading to increased wall stress and progressive dilatation, commonly associated with atherosclerotic coronary artery disease.
Observation:
- A 60-year-old male with hypertension presented with symptoms of an inferior wall myocardial infarction.
- Transthoracic echocardiography initially identified an intramyocardial mass, prompting further investigation.
- The observed mass was subsequently diagnosed as a thrombosed right coronary artery aneurysm.
Findings:
- The case illustrates a thrombosed coronary artery aneurysm mimicking an intramyocardial mass.
- Atherosclerotic coronary artery disease is the primary etiology for most coronary artery aneurysms.
- While rupture is possible, thrombosis and hematoma formation are more common complications, leading to diagnostic challenges.
Implications:
- Accurate diagnosis of coronary artery aneurysms is crucial, especially when they present as intramyocardial masses.
- Echocardiography can be an initial tool, but advanced imaging may be necessary for definitive diagnosis.
- Understanding the potential for coronary artery aneurysms to mimic other cardiac pathologies is vital for appropriate patient management.
Abstract:
A coronary artery aneurysm is defined as coronary dilatation that exceeds the diameter of normal adjacent artery segments, or is 1.5 times the diameter of the largest coronary artery. Coronary artery aneurysms are rare with an incidence of between 1.5% to 5%. The aneurysm is caused by destruction of the vessel media, thinning of the arterial wall, increased wall stress, and progressive dilatation of a segment of the coronary artery. The most common cause is atherosclerotic coronary artery disease. These aneurysms occasionally rupture but more commonly develop thrombus and hematoma leading to the appearance of the presence of an intramyocardial mass. We present the case of a 60-year-old man with hypertension who presented with a mass that was identified initially by transthoracic echocardiography in the setting of an inferior wall myocardial infarction, which was later recognized to be a thrombosed right coronary artery aneurysm.
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