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Updated: Aug 20, 2026
Immunostimulatory Agent Evaluation: Lymphoid Tissue Extraction and Injection Route-Dependent Dendritic Cell Activation
Published on: September 16, 2018
[The extraction and effects on mouse lymphocyte proliferation of immunoregulation components from Lysimachia
Lanling Zhang1, Jiming Meng, Haisheng Chen
1Department of Rheumatology, Changhai Hospital, Second Military Medical University, Shanghai.
Objective:
To study the effects of extracted fractions from the whole plants of Lysimachia hemsleyana Maxim on the proliferation ability of lymphocytes in mice in vitro.
Methods:
We extracted the components by using of ethanol, ether from petroleum, chloroform, ethyl acetate and n-butanol, successively then study them on the proliferation of lymphocytes in mice.
Results:
The n-butanol fraction obviously inhibited the proliferation of spleen lymphocytes induced by LPS, bilaterally regulated the T lymphocyte proliferation induced by ConA. The chloroform fraction markedly enhanced the lymphocytes proliferation induced by ConA or LPS.
Conclusion:
The results suggested that n-butanol fraction and chloroform fraction from Lysimachia hemsleyana possibly maybe have immunoregulation effects.
