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Updated: Aug 20, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Evaluation of genetic substructure in the Irish Study of High-Density Schizophrenia Families
Patrick F Sullivan1, Dermot Walsh, F Anthony O'Neill
1University of North Carolina at Chapel Hill, Department of Genetics, 27599-7264, USA. pfsulliv@med.unc.edu
Abstract:
The presence of genetic substructure has the potential to diminish the chances of detecting a linkage signal. Using a Markov chain Monte Carlo procedure developed by Pritchard and colleagues and implemented in the program STRUCTURE, we evaluated the evidence for genetic substructure using genotypes from 37 microsatellite markers in affected individuals selected at random from 263 multiplex families in the Irish Study of High-Density Schizophrenia Families. We found no evidence for the presence of genetic substructure in this sample.
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