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Updated: Aug 20, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
Published on: September 3, 2013
Dielectrophoresis of nanoparticles
Arun T J Kadaksham1, Pushpendra Singh, Nadine Aubry
1Department of Mechanical Engineering, New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA.
Abstract:
A numerical scheme based on the distributed Lagrange multiplier method (DLM) is used to study the motion of nano-sized particles of dielectric suspensions subjected to uniform and nonuniform electric fields. Particles are subjected to both electrostatic and hydrodynamic forces, as well as Brownian motion. The results of the simulations presented in this paper show that uniform electric fields the evolution of the particle structures depends on the ratio of electrostatic particle-particle interactions and Brownian forces. When this ratio is of the order of 100 or greater, particles form stable chains and columns, whereas when it is of the order of 10 or smaller the particle distribution is random. For the nonuniform electric field cases considered in this paper, the relative magnitude of Brownian forces is in the range such that it does not influence the eventual collection of particles by dielectrophoresis and the particular locations where the particles are collected. However, Brownian motion is observed to influence the transient particle trajectories. The deviation of the particle trajectories compared to those determined by the electrostatic and hydrodynamic forces alone is characterized by the ratio of Brownian and dielectrophoretic forces.
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