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53-years-old with mental status changes.

M Obadah Al Chekakie¹, M Luay Al Kotoub, Craig Nielsen

¹Internal Medicine Residency Program/NA21, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

Comprehensive Therapy

|November 30, 2004

Summary

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D-lactic acidosis, a complication of short bowel syndrome, causes neurological symptoms and metabolic acidosis. Treatment involves hydration, nutritional support, and antibiotics, while prevention focuses on diet and supplements.

Area of Science:

Biochemistry
Gastroenterology
Neurology

Background:

Short bowel syndrome (SBS) can lead to malabsorption and subsequent complications.
D-lactic acidosis is a recognized, albeit less common, metabolic derangement in SBS patients.

Observation:

Patients with SBS may present with neurological deficits and metabolic acidosis.
The presence of D-lactic acid in the blood is a key indicator.

Findings:

D-lactic acidosis manifests with diverse neurological symptoms and metabolic acidosis.
Effective management includes fluid resuscitation, nutritional repletion, and targeted antibiotic therapy.

Implications:

Understanding D-lactic acidosis is crucial for managing SBS complications.

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Dietary modifications and supplementation are vital for preventing recurrence.