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Updated: Jun 4, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
[Effects of ureteral stents on rabbit upper urinary tract urodynamics]
De-feng Qi1, Kai-jun Wu, Xun Li
1Center of Minimal Invasive Surgery, First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510230, China. qdf70818@tom.com
Objective:
To explore the effects of ureteral stent placement on ureteral peristalsis and the time course of renal pelvic pressure changes.
Method:
Forty rabbits were randomized equally into 8 groups, including a control group without placement of ureteral stents. The other 7 groups received ureteral stent placement, which were retained for 0, 1, 2, 3, 4, 7, and 12 weeks respectively. When the rabbits were bred for the specified time periods, ureteral peristalsis was observed and renal pelvic pressure measured.
Result:
The renal pelvic pressure was initially increased after the stent placement, but then followed by gradual decreases. Ureteral peristalsis was not observed after the stent placement.
Conclusion:
Ureteral stent is a factor for causing obstruction in normal ureter.
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