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Updated: Aug 20, 2026

Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization
Published on: July 15, 2020
Photoacoustic imaging of blood vessels with a double-ring sensor featuring a narrow angular aperture
Roy G M Kolkman1, Erwin Hondebrink, Wiendelt Steenbergen
1University of Twente, Biophysical Engineering, Faculty of Science and Technology, P.O. Box 217, 7500 AE Enschede, The Netherlands. r.g.m.kolkman@utwente.nl
Abstract:
A photoacoustic double-ring sensor, featuring a narrow angular aperture, is developed for laser-induced photoacoustic imaging of blood vessels. An integrated optical fiber enables reflection-mode detection of ultrasonic waves. By using the cross-correlation between the signals detected by the two rings, the angular aperture of the sensor is reduced by a factor of 1.9, from 1.5 to 0.8 deg. Consequently, photoacoustic images could be obtained in a manner analogous to the ultrasound B-scan mode. Next, the cross section of artificial blood vessels is visualized by reconstruction of the absorbed energy distribution. Finally, in vivo imaging and the subsequent reconstruction of the absorbed energy distribution is demonstrated for superficial blood vessels in the human wrist.

