Related Experiment Video
Updated: Aug 11, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
Published on: December 16, 2013
Statistical mechanical approach to competitive binding of metal ions to multi-center receptors
Michal Borkovec1, Josef Hamácek, Claude Piguet
1Department of Inorganic, Analytical, and Applied Chemistry, University of Geneva, 30 Quai Ernest-Ansermet, 1211, Geneva 4, Switzerland. michal.borkovec@unige.ch
Abstract:
A microscopic site binding model to treat binding of several metal ions to multi-center receptors is proposed. The model introduces the appropriate parameterization in terms of microscopic complexation constants and metal-metal pair interaction energies. The model is solved with statistical mechanical techniques, including direct enumeration or transfer matrices. We obtain microscopic and macroscopic complexation constants, microstate probabilities, and binding isotherms for chain-like receptors, including the long-chain limit. Various examples to illustrate the usefulness of the model are given.
More Related Videos
07:54Analysis of AtHIRD11 Intrinsic Disorder and Binding Towards Metal Ions by Capillary Gel Electrophoresis and Affinity Capillary Electrophoresis
Published on: August 22, 2018
11:04Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
Published on: September 7, 2019
Related Concept Videos
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
The Equilibrium Binding Constant and Binding Strength
Ligand Binding and Linkage
The Equilibrium Binding Constant and Binding Strength
Complexation Equilibria: Overview
The equilibrium constant of the complexation reaction is represented as the formation constant...
Complexation Equilibria: The Chelate Effect