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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
Published on: July 4, 2016
NO spin trapping and EPR studies on the photochemistry of aliphatic aldehydes
Fan Wang1, Liandi Lei, Longmin Wu
1State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Abstract:
Radicals, such as acyl, hydrated acyl, alkyl and ketyl radicals, from aliphatic aldehyde photochemistry were detected by NO spin trapping and EPR techniques. Deuterium effects on EPR spectra and the generation of radicals by 2-amido-2-propyl radical attack on substrate molecules in aqueous solution via hydrogen-atom abstraction were applied to identify radicals produced photochemically from aldehydes. Aliphatic aldehydes used in the present investigation were formaldehyde, acetaldehyde, acetaldehyde-d4, propionaldehyde, isobutyraldehyde, isopentanal and tert-pentanal. Possible reaction mechanisms are suggested.
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