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[Lack of association between blood pressure variability and left ventricular hypertrophy in essential hypertension]

Elisenda Gómez Angelats1, Cristina Sierra, Antonio Coca

  • 1Unidad de Hipertensión, Servicio de Medicina Interna, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona (IDIBAPS), Barcelona, Spain.

Medicina Clinica
|December 3, 2004
PubMed

Insights

Blood pressure variability is not linked to left ventricular hypertrophy in essential hypertension. Higher systolic blood pressure, not its fluctuations, correlates with left ventricular hypertrophy.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Diagnostic Imaging

Context:

  • Essential hypertension is a common condition.
  • Left ventricular hypertrophy (LVH) is a significant complication of hypertension.
  • The role of blood pressure (BP) variability in LVH development is debated.

Purpose:

  • To investigate the association between BP variability and LVH in essential hypertensive patients.
  • To compare BP variability using beat-to-beat finger monitoring and ambulatory blood pressure monitoring (ABPM).

Summary:

  • This study analyzed 43 untreated hypertensive patients, assessing BP variability and LVH via echocardiography.
  • LVH was present in 70% of patients.
  • Higher office, 24-hour ambulatory, and continuous finger systolic BP were observed in patients with LVH.
  • No significant differences in BP variability metrics (nocturnal fall, standard deviation) were found between groups.

Impact:

  • Findings suggest that the severity of systolic BP elevation, rather than BP variability, is primarily associated with LVH in essential hypertension.
  • This research clarifies the relationship between BP dynamics and cardiac remodeling in hypertensive individuals.
Abstract

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