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Cardiovascular late effects
Dawn M Greving1, Sheila Judge Santacroce
1Hematology/Oncology Division, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA. dawn.greving@cchmc.org
Summary
Childhood cancer survivors treated with radiation or chemotherapy face increased cardiovascular risks. Pediatric oncology nurses play a vital role in managing these long-term heart health effects.
Area of Science:
- Pediatric Oncology
- Cardiovascular Health
- Cancer Survivorship
Background:
- Childhood cancer treatments, including radiation therapy and chemotherapy, can lead to significant long-term health issues.
- Cardiovascular late effects are a major concern for survivors, impacting quality of life and longevity.
Purpose of the Study:
- To review the spectrum of cardiovascular late effects in childhood cancer survivors.
- To identify factors influencing the development of these cardiovascular issues.
- To explore the role of pediatric oncology nurses in mitigating these risks.
Main Methods:
- Integrative literature review.
- Synthesis of existing research on cardiovascular late effects.
- Analysis of risk factors and nursing interventions.
Main Results:
- Survivors treated with radiation (especially involving the heart or hypothalamic-pituitary axis) and specific chemotherapies exhibit higher risks.
- Younger age at diagnosis, longer time since treatment, and family history of heart disease exacerbate these risks.
- Cardiovascular risk factors and diseases are prevalent in this population.
Conclusions:
- Pediatric oncology nurses are crucial in promoting cardiovascular health throughout survivorship.
- Early identification and management of cardiovascular risks are essential for childhood cancer survivors.
- Interventions aimed at minimizing late effects can improve long-term outcomes.