Introducing a 4th dimension to protein-protein docking

The RNA-binding protein PRRC2B preserves 5' TOP mRNA during starvation to maintain ribosome biogenesis during nutrient recovery.

Nucleic acids research·2025

Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor.

Life science alliance·2023

Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins.

Chemical science·2023

Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction.

Autophagy·2023

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.

Biological chemistry·2022

Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions.

Molecular systems biology·2022

Cryo-EM structures of human caspase-4 in complex with full-length gasdermin D.

Structure (London, England : 1993)·2026

Structures of the Xcp and Hxc T2SS endopili provide new insights into type IV pili subfamilies.

Structure (London, England : 1993)·2026

Structure of Perinereis linea erythrocruorin reveals a compact extracellular globin megacomplex.

Structure (London, England : 1993)·2026

Meet the author: Stephen Brohawn.

Structure (London, England : 1993)·2026

Tetraspanins bring Norrin into focus: Structural insights into ligand-specific Wnt signaling.

Structure (London, England : 1993)·2026

Uncovering subtype-selective activation of the K<sub>Ca</sub>3.1 channel by SKA-111.

Structure (London, England : 1993)·2026

Generalizable structure-function covariation predictive of antidepressant response revealed by target-oriented multimodal fusion.

Nature. Mental health·2026

Integrated docking-molecular dynamics, ADME-toxicity profiling, and transcriptomic validation identify oroxylin a as a TLR7-targeting flavonoid candidate in systemic lupus erythematosus.

Frontiers in chemistry·2026

Novel seleno-ureido hybrids targeting head and neck cancer and beyond: design, synthesis, and apoptosis-mediated anticancer evaluation.

RSC advances·2026

Can Large Language Models Translate MS/MS into Molecular Caption?

Analytical chemistry·2026

Synthesis, Characterization, and Biological Evaluation of Co(II), Cu(II), and Ni(II) Complexes With 2,2'-Bipyridine-5,5'-Dicarboxamide Ligands: Antibacterial and Enzyme Inhibition Studies.

ChemistryOpen·2026

Evaluation of deep learning architectures for predicting ligand interactions with neurologically relevant GPCRs.

Journal of cheminformatics·2026

Related Experiment Videos

Introducing a 4th dimension to protein-protein docking

Related Concept Videos

The RNA-binding protein PRRC2B preserves 5' TOP mRNA during starvation to maintain ribosome biogenesis during nutrient recovery.

Loss-of-function cancer-linked mutations in the EIF4G2 non-canonical translation initiation factor.

Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins.

Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction.

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.

Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions.

Cryo-EM structures of human caspase-4 in complex with full-length gasdermin D.

Structures of the Xcp and Hxc T2SS endopili provide new insights into type IV pili subfamilies.

Structure of Perinereis linea erythrocruorin reveals a compact extracellular globin megacomplex.

Meet the author: Stephen Brohawn.

Tetraspanins bring Norrin into focus: Structural insights into ligand-specific Wnt signaling.

Uncovering subtype-selective activation of the K<sub>Ca</sub>3.1 channel by SKA-111.

Generalizable structure-function covariation predictive of antidepressant response revealed by target-oriented multimodal fusion.

Integrated docking-molecular dynamics, ADME-toxicity profiling, and transcriptomic validation identify oroxylin a as a TLR7-targeting flavonoid candidate in systemic lupus erythematosus.

Novel seleno-ureido hybrids targeting head and neck cancer and beyond: design, synthesis, and apoptosis-mediated anticancer evaluation.

Can Large Language Models Translate MS/MS into Molecular Caption?

Synthesis, Characterization, and Biological Evaluation of Co(II), Cu(II), and Ni(II) Complexes With 2,2'-Bipyridine-5,5'-Dicarboxamide Ligands: Antibacterial and Enzyme Inhibition Studies.

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Introducing a 4th dimension to protein-protein docking

Related Concept Videos

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