Related Experiment Video
Updated: Aug 20, 2026

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
New norditerpenoids with trypanocidal activity from Vitex trifolia
Fumiyuki Kiuchi1, Kenji Matsuo, Michiho Ito
1Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences, Hachiman-dai, Tsukuba, Japan.
Abstract:
Trypanocidal constituents of the fruits of Vitex trifolia were investigated. Activity-guided isolation of the acetone extract resulted in the isolation of two new norditerpene aldehydes, 1 and 2, together with five known diterpenes: vitexifolin E (3), vitexifolin F (4), vitexilactone (5), 6-acetoxy-9-hydroxy-13(14)-labden-16,15-olide (6), and previtexilactone (7). In vitro minimum lethal concentrations of the isolated compounds against epimastigotes of Trypanosoma cruzi were 11 microM (1), 36 microM (2), 34 microM (3), 34 microM (4), 66 microM (5), 66 microM (6), and >265 microM (7).
Related Concept Videos
Antifungal Agents
Antiprotozoal Agents
Anthelminthic Agents
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
