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Updated: Aug 3, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
[Prevention of type 2 diabetes--an overview]
1Seksjon for endokrinologi, Medisinsk avdeling, St. Olavs Hospital, 7006 Trondheim. elisabeth.qvigstad@stolav.no
Background:
The incidence of type 2 diabetes is increasing. Epidemiological data indicate a need to investigate possible interventions to prevent or delay the onset.
Methods:
Diabetologic and pharmacologic information was retrieved from review papers. Additionally, the Cochrane library and PubMed were searched for relevant studies.
Results:
Recent studies have demonstrated the efficacy of lifestyle intervention and metformin treatment in impaired glucose tolerance. Surgical treatment for obesity could be beneficial for individuals with BMI > 35. Recommendations from the American Diabetes Association for the prevention of type 2 diabetes are opportunistic screening, intervention on lifestyle factors such as physical activity and weight reduction, and also on cardiovascular risk factors.
Interpretation:
"Prediabetes" should be identified and treated by lifestyle intervention in primary health care. National guidelines for primary prevention should also be established.
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