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Assembly-disassembly of the nuclear lamina
1Swiss Institute for Experimental Cancer Research, Epalinges.
Current Opinion in Cell Biology
|February 1, 1992
Abstract:
Recently, progress in the study of lamins has been made in three areas: signals required for targetting newly synthesized lamins to the correct subnuclear compartment have been identified; information on lamina assembly has been obtained from in vitro studies using bacterially expressed proteins; and a mechanistic explanation for how the nuclear lamina is diassembled at the onset of mitosis is emerging.